iSenseDNA
iSenseDNA will herness tailor-made circular supercoiled DNA as "transducers" and its dynamical interactions with proteins as an unprecedented and disruptive approach in real-time bio-molecular sensing that can transform medical diagnostics and treatment.
The consortium
iSenseDNA is multidisciplinary with partners from universities, research institutes and an ambitious SME.
iSenseDNA aims at developing an innovative technology, based on tailor-made DNA structures, as an ‘ad-hoc’ tool for real-time advanced optical analysis of biomolecules ‘in action’
Challenge
Understanding the function of biomolecules during complex biological processes is the grand-challenge in structural biology. iSenseDNA focuses on developing a technology to identify what a change in molecular structure implies about its function.
Impact
iSenseDNA will provide a revolutionary technology for next-generation nano-biosensing, sensitive to target in real-time conformational changes and link molecular structure and biological function.
Outputs
Our research findings will be open access and they will be listed on this website. Meanwhile, an overview of publications by the partners relevant to iSenseDNA is available, as well as other media related to the project.
Project details
TITLE: Computation driven development of novel in vivo-like-DNA-nanotransducers for biomolecules structure identification
Grant Agreement: 101046920
START-END: October the 1st 2022– September the 30th 2026
EU CONTRIBUTION: €3.000.419,00
TOPIC: EIC Pathfinder Open